abstract：:Depression is a major public health problem affecting about 12% of the world population. Drugs exist but they have many side effects. In the last few years, natural substances (e.g. flavonoids) have been tested to cure such disorders. Cocoa polyphenolic extract is a complex compound prepared from non-roasted cocoa bea...

journal_title：Nutritional neuroscience

authors： Messaoudi M,Bisson JF,Nejdi A,Rozan P,Javelot H

更新日期：2008-12-01 00:00:00

abstract：:We compared the maturation of the monosynaptic stretch reflex in control rats and in rats submitted to neonatal malnutrition. Electrical stimulations of the sciatic nerve were applied in wakeful rats of different ages (21-90 days) to record, by surface electrodes, the maximal direct motor response (M(max)) or the maxi...

journal_title：Nutritional neuroscience

authors： Freitas-Silva SR,Manhães-de-Castro R,Pérot C

更新日期：2008-10-01 00:00:00

abstract：:This symposium examined current trends in neuroscience and developmental psychology as they apply to assessing the effects of nutrients on brain and behavioral development of 0-6-year-olds. Although the spectrum of nutrients with brain effects has not changed much in the last 25 years, there has been an explosion in n...

journal_title：Nutritional neuroscience

authors： Rosales FJ,Zeisel SH

更新日期：2008-06-01 00:00:00

abstract：:Pseudotumor cerebri occurs quite rarely in the pediatric population and its clinical features differ from adults in many ways. Intracranial hypertension with papilledema should obviously be treated promptly to avoid permanent visual damage, but various more or less invasive options have been proposed over the years, f...

journal_title：Nutritional neuroscience

authors： Marton E,Feletti A,Mazzucco GM,Longatti P

更新日期：2008-02-01 00:00:00

abstract：:Nutritional imbalances were produced by varying litter size pups per dam: 3 (small), 6 (medium), and 12 (large). On the 21st day, 4 subjects of each litter, were sacrificed and the remaining were grouped, 2 per cage, with or without running wheels, with food and water ad libitum. Adult subjects were tested in water ma...

journal_title：Nutritional neuroscience

authors： Viana LC,Torres JB,Farias JA,Kawhage R,Lins N,Passos A,Quintairos A,Trévia N,Guedes RC,Diniz CW

更新日期：2007-10-01 00:00:00

abstract：:Carnosine (beta-alanyl-L-histidine) and its derivative anserine (beta-alanyl-1-methyl-L-histidine) are antioxidants and putative neurotransmitters in the brain. These dipeptides are rich in the commercially available supplement chicken breast extract (CBEX). To clarify the effects of CBEX on the brain, we examined whe...

journal_title：Nutritional neuroscience

authors： Tomonaga S,Hayakawa T,Yamane H,Maemura H,Sato M,Takahata Y,Morimatsu F,Furuse M

更新日期：2007-06-01 00:00:00

abstract：:Given that protein malnutrition induces structural, neurochemical and functional changes in the CNS, the present study aimed to investigate the effects of different early periods of protein malnutrition on the behavior and reactivity to diazepam (DZ) in a model of anxiety: the fear-potentiated startle (FPS). Male Wist...

journal_title：Nutritional neuroscience

authors： Françolin-Silva AL,Brandão ML,Almeida SS

更新日期：2007-02-01 00:00:00

abstract：:The effects of perinatal undernutrition on the number of neurons and apoptotic cells of the locus coeruleus (LC) of female and male rats at postpartum days 7, 12, 20, 30 and 60 were studied. Undernutrition reduces the number of neurons in both sexes without affecting cell death, as indicated by the ratio of apoptotic ...

journal_title：Nutritional neuroscience

authors： Pinos H,Collado P,Salas M,Pérez-Torrero E

更新日期：2006-10-01 00:00:00

abstract：:We investigated the components of ginger that are involved in increasing body temperature. Gingerols ([6,8,10]-gingerols) and shogaols ([6,8,10]-shogaols) having different alkyl carbon chain lengths were targeted. All the gingerols and shogaols increased intracellular calcium concentration in rat transient receptor po...

journal_title：Nutritional neuroscience

authors： Iwasaki Y,Morita A,Iwasawa T,Kobata K,Sekiwa Y,Morimitsu Y,Kubota K,Watanabe T

更新日期：2006-06-01 00:00:00

abstract：:Newborn rats maintain mother-litter bonds by using olfactory signals. At birth, units in the olfactory glomeruli (OG) are immature and vulnerable to noxious epigenetic factors like undernutrition. Because little is known about the effects of neonatal undernutrition upon the OG morphological organization, different OG ...

journal_title：Nutritional neuroscience

authors： Frias C,Torrero C,Regalado M,Salas M

更新日期：2006-02-01 00:00:00

abstract：:The aim of this study was to examine the function of the lateral parabrachial area (LPB) in relation to the intragastric administration of nutrients. The consumption of flavors associated with intragastric nutrient administration and the subsequent food and water intake were measured in rats with lesions in the LPB. T...

journal_title：Nutritional neuroscience

authors： Zafra MA,Simón MJ,Molina F,Puerto A

更新日期：2005-10-01 00:00:00

abstract：:Sensory awareness contributes to the enjoyment of eating and drinking. This study tested the hypothesis that changes in the intensity of oral sensations could be used to regulate the volume of intake. Forty women (< 36 years) volunteered. The participants consumed distilled water, salt water and two concentrations of ...

journal_title：Nutritional neuroscience

authors： Poothullil JM

更新日期：2005-08-01 00:00:00

abstract：:Mitochondrial decay due to oxidative damage is a contributor to brain aging and age-related neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). One type of mitochondrial decay is oxidative modification of key mitochondrial enzymes. Enzyme dysfunction, that is due to poor binding ...

journal_title：Nutritional neuroscience

authors： Liu J,Ames BN

更新日期：2005-04-01 00:00:00

abstract：:This study examined effects of a single protein-free (PROT-free), high carbohydrate meal (0% protein, 82% carbohydrate) or control meal (20% protein, 62% carbohydrate) on coping behavior and neurotransmitter levels of male Fischer 344 rats. Meals varying in protein/carbohydrate ratio differentially affect transport of...

journal_title：Nutritional neuroscience

authors： Yeghiayan SK,Georgelis JH,Maher TJ,Lieberman HR

更新日期：2004-10-01 00:00:00

abstract：:Endogenous neuropeptide Y (NPY) levels increase during fasting and before dark onset in rats. The feeding that follows these states elicits the release of serotonin in the lateral hypothalamus (LH), as part of the physiological mechanisms controlling satiety. With the hypothesis that exogenous NPY-induced feeding shou...

journal_title：Nutritional neuroscience

authors： Mori RC,Telles MM,Guimarães RB,Novo NF,Juliano Y,Nascimento CM,Ribeiro EB

更新日期：2004-08-01 00:00:00

abstract：:This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings. The SD was recorded continuously for 3-4h in 13 well-nourished (W)...

journal_title：Nutritional neuroscience

authors： De Vasconcelos CA,De Oliveira JA,De Oliveira Costat LA,Guedes RC

更新日期：2004-06-01 00:00:00

abstract：:Rats given long-term access to a palatable sucrose solution are more sensitive to (1) the analgesic potency of morphine and (2) the anorectic actions of naltrexone. In the present experiment, the ability of naltrexone to antagonize the antinociceptive properties of morphine was examined in sucrose- and chow-fed rats. ...

journal_title：Nutritional neuroscience

authors： D'Anci KE,Kanarek RB

更新日期：2004-02-01 00:00:00

abstract：:Moderately low-protein diets lead to a rapid increase in food intake and body fat. The increase in feeding is associated with a decrease in the concentration of serum urea nitrogen, suggesting that the low-protein-induced increase in food intake may be related to the decreased metabolism of nitrogen from amino acids. ...

journal_title：Nutritional neuroscience

authors： White BD,Du F,Higginbotham DA

更新日期：2003-12-01 00:00:00

abstract：:Cognitive and motor performance are critical in many circumstances and are impaired by sleep deprivation. We administered placebo, tyrosine 150 mg/kg, caffeine 300 mg/70 kg, phentermine 37.5 mg and D-amphetamine 20 mg at 15.30 h following overnight sleep deprivation and compare their effects on cognitive and motor per...

journal_title：Nutritional neuroscience

authors： Magill RA,Waters WF,Bray GA,Volaufova J,Smith SR,Lieberman HR,McNevin N,Ryan DH

更新日期：2003-08-01 00:00:00

abstract：:Apelin, the endogenous peptide ligand of the APJ receptor, is expressed in brain regions implicated in food and water intake. This study reports for the first time, the effect of apelin-12, one of the most potent apelin peptides, on spontaneous (nocturnal) feeding. Randomised intracerebroventricular injection of 1, 3 ...

journal_title：Nutritional neuroscience

authors： O'Shea M,Hansen MJ,Tatemoto K,Morris MJ

更新日期：2003-06-01 00:00:00

abstract：:In this article, the second of a series on the analysis of time to event data, we address the case in which multiple predictors (covariates) that may influence the time to an event are taken into account. The hazard function is introduced, and is given in a form useful for assessing the impact of multiple covariates o...

journal_title：Nutritional neuroscience

authors： Mera R,Thompson HW,Prasad C

更新日期：2003-04-01 00:00:00

abstract：:Primary brain injury in stroke is followed by an excitotoxic cascade, oxidative stress and further neural damage. Glutathione is critical and depleted in oxidative stress. Since cysteine is limiting in glutathione synthesis, this study investigated the effect of dietary sulfur amino acid (SAA) deficiency on neural dam...

journal_title：Nutritional neuroscience

authors： Bobyn PJ,Franklin JL,Wall CM,Thornhill JA,Juurlink BH,Paterson PG

更新日期：2002-12-01 00:00:00

abstract：:Food intake decreases and a conditioned taste aversion is induced when rats are fed a diet that is devoid of an indispensable amino acid. The purpose of this study was to characterize the meal patterns associated with (1) the onset of anorexia after the initial recognition of a threonine deficiency and (2) after the d...

journal_title：Nutritional neuroscience

authors： Feurté S,Tomé D,Gietzen DW,Even PC,Nicolaïdis S,Fromentin G

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:The Mediterranean diet has been postulated as a protective factor against different diseases including stroke. Thus, an epidemiological study in a Mediterranean country, such as Spain, focused on diet may offer new insights of the potential benefits of this nutritional pattern to prevent the onset of cerebrovas...

journal_title：Nutritional neuroscience

authors： Martínez-González MA,Sanchez-Villegas A,De Irala J,Marti A,Martínez JA

更新日期：2002-02-01 00:00:00

abstract：:Phosphatidylserine (PS) is a phospholipid widely sold as a nutritional supplement. PS has been claimed to enhance neuronal membrane function and hence cognitive function, especially in the elderly. We report the results of a clinical trial of soybean-derived PS (S-PS) in aging subjects with memory complaints. Subjects...

journal_title：Nutritional neuroscience

authors： Jorissen BL,Brouns F,Van Boxtel MP,Ponds RW,Verhey FR,Jolles J,Riedel WJ

更新日期：2001-01-01 00:00:00

abstract：:Dietary sulfur amino acid content is a major determinant of glutathione concentration in some tissues. We examined whether brain glutathione (GSH), a key component of antioxidant defense important for minimizing ischemic injury, was also responsive to short-term sulfur amino acid deficiency. Female Long-Evans adult ra...

journal_title：Nutritional neuroscience

authors： Paterson PG,Lyon AW,Kamencic H,Andersen LB,Juurlink BH

更新日期：2001-01-01 00:00:00

abstract：:Most previous research has focused on the effects of single neurotransmitters and neuropeptides on ingestive behavior. An important next step in the advancement of the science of ingestive behavior is to gain an understanding of how these different systems interact with one another. The present article is designed as ...

journal_title：Nutritional neuroscience

authors： Roth JD,Rowland NE

更新日期：2000-01-01 00:00:00

abstract：:Young children respond to energy dilution achieved using fat or sugar substitutes by compensating for reduced energy within a single meal. The ability to respond to energy dilution in the short term may diminish with age, since adults do not reliably demonstrate accurate caloric compensation in the short term. Two exp...

journal_title：Nutritional neuroscience

authors： Hetherington MM,Wood C,Lyburn SC

更新日期：2000-01-01 00:00:00

abstract：:We examined Dohan's hypothesis that schizophrenia is associated with the absorption of "exorphins" contained in gluten and casein. In addition, because of the work of Reichelt et al. (Reichelt, K.L., Saelid, G., Lindback, J. and Orbeck, H. (1986) Biological Psychiatry 21:1279-1290) and Rodriguez et al. (Rodriguez, Tra...

journal_title：Nutritional neuroscience

authors： Cade R,Privette M,Fregly M,Rowland N,Sun Z,Zele V,Wagemaker H,Edelstein C

更新日期：2000-01-01 00:00:00

abstract：:The kynurenine (KYN) pathway of tryptophan metabolism produces several neuroactive metabolites, including 3-hydroxykynurenine (3HK). The pathway is subject to regulation by a number of effectors including pregnancy and availability of vitamin B-6. Vitamin B-6 depleted humans and animals excrete abnormally high concent...

journal_title：Nutritional neuroscience

authors： van de Kamp JL,Smolen A

更新日期：2000-01-01 00:00:00

abstract：:Mice and rats exposed to a maternal diet high in fat have an increased risk of reproductive system tumors later in life. To test whether a part of the hypothalamus associated with sex differentiation, the sexually dimorphic nucleus of the preoptic area (SDN-POA), might be involved, this nucleus was measured in the off...

journal_title：Nutritional neuroscience

authors： Walker BE

更新日期：1999-01-01 00:00:00

abstract：:The effects of prenatal cocaine and protein malnutrition were examined on acquisition of the radial arm maze in adult male Sprague-Dawley rats whose mothers were provided with a 6% casein, a 25% casein or a standard chow diet and cocaine (30mg/kg) or saline injections beginning 5 weeks prior to mating and continuing t...

journal_title：Nutritional neuroscience

authors： Shumsky JS,Shultz PL,Galler JR,Tonkiss J

更新日期：1999-01-01 00:00:00

abstract：:While there are many theories on the control of feeding behavior that emphasize a role for energy substrates and their metabolism, the mechanism that couples changes in energy substrate supply and metabolism to alterations in food intake remains unclear. The purpose of the present project was to investigate the possib...

journal_title：Nutritional neuroscience

authors： Bounds JK,Adloo AA,Harp PR,Olivier K,Roane DS

更新日期：1999-01-01 00:00:00

abstract：:The effects of iodine deficiency on growth and development are known as the iodine deficiency disorders (IDDs). Most common is goitre at all ages, but most significant are the effects on brain development during pregnancy. The major effect of iodine deficiency is the clinical syndrome of endemic cretinism characterise...

journal_title：Nutritional neuroscience

authors： Hetzel BS

更新日期：1999-01-01 00:00:00

abstract：:The effects of noise-induced arousal on chewing, subjective motivation to eat, the pleasantness of sweet food, and food intake were investigated. Twenty-four healthy normal weight male subjects received cookies differing in sucrose content (2%, 11%, 18% or 27%) before, during, and after 10 min of intermittent white no...

journal_title：Nutritional neuroscience

authors： Macht M

更新日期：1998-01-01 00:00:00

abstract：:Adult female rats, receiving a low protein diet at perinatal age and then recovered with balanced chow (D rats), were evaluated in the Open Field Drink Test (OFDT), after different acute and chronic treatments with benzodiazepines (BZD) ligands, as compared with control (C) female rats. Control and D rats showed simil...

journal_title：Nutritional neuroscience

authors： Borghese CM,Córdoba NE,Arolfo MP,Orsingher OA

更新日期：1998-01-01 00:00:00

abstract：:The treatment of resistant depression has involved the use of various adjuncts in addition to the antidepressant, such as lithium or liothyronine (T3). This case report describes a woman with a history of chronic depression (dysthymic disorder), unresponsive to a number of traditional antidepressants, who was treated ...

journal_title：Nutritional neuroscience

authors： Vadnal R

更新日期：1998-01-01 00:00:00

abstract：:The objective of this study was to determine whether an essential fatty acid (EFA)-deficient diet (saturated fat) fed during development would alter the pattern of dendritic growth in pyramidal neurons of mouse occipital cortex. Pregnant and lactating mice were fed either a saturated fat or control diet throughout pre...

journal_title：Nutritional neuroscience

authors： Wainwright PE,Bulman-Fleming MB,Lévesque S,Mutsaers L,McCutcheon D

更新日期：1998-01-01 00:00:00

abstract：:A debate is open in the literature concerning the safety of low (dietary) versus high (intoxicating or addicting) alcohol consumption. Epidemiological data do indeed suggest that moderate ethanol intake may have beneficial effects, at least at cardiovascular level. On the other hand there are few data on the effect of...

journal_title：Nutritional neuroscience

authors： Battaini F,Pascale A,Ancona DM,Cagiano R,Cuomo V,Govoni S

更新日期：1998-01-01 00:00:00